Plasma Concentration of Mepivacaine in Pediatric Patients with Postoperative-epidural Analgesia.

Pediatric epidural analgesia (PEA).

The pediatric epidural is an accepted method of advanced analgesia in children. Newer techniques have now superseded pediatric epidural analgesia (PEA), being as effective and safer, especially with the advances in ultrasonography. PEA is, however, still an important technique to master and employ, and it may be that the indications for this mode of analgesia have now become more defined.

Epidural naloxone reduces postoperative nausea and vomiting in patients receiving epidural sufentanil for postoperative analgesia.

BACKGROUND Epidural opioids have excellent analgesic properties, but their side-effects limit their use in patient-controlled epidural analgesia. This study was designed to evaluate the effect of epidural naloxone on the side-effects of sufentanil, focusing on postoperative nausea and vomiting (PONV) in patients undergoing total knee replacement (TKR). METHODS After obtaining Institutional Re...

Epidural ketamine for postoperative analgesia.

·T WO factors have increased interest in ketamine for postoperative analgesia. The first was the discovery of the N-Methyl-D-aspartate (NMDA) receptor and its role in central pain processing and spinal cord neural plasticity.1 Ketamine is one of two clinically useful NMDA receptor antagonists available (the other is dextromethorphan). Ketarnine binds non-competitively to the PCI, (phencyclidine...

Epidural ketamine for postoperative analgesia

T WO factors have increased interest in ketamine for postoperative analgesia. The first was the discovery of the N-Methyl-D-asparrate (NMDA) receptor and its role in central pain processing and spinal cord neural plasticity. 1 Ketamine is one of two clinically useful NMDA receptor antagonists available (the other is dextromethorphan). Ketamine binds non-competitively to the PCI, (phencyclidine)...

Epidural Analgesia in the Postoperative Period